Uji Kandungan Alkaloid pada Bubuk Kayu Manis  ( Cinnamomum burmannii) dengan Metode Sokletasi

Chaterine Juliana Sitorus; Greace Astrid Rotua Hutabarat

doi:10.59581/konstanta.v2i2.3367

Authors

Chaterine Juliana Sitorus Universitas Negeri Medan
Greace Astrid Rotua Hutabarat Universitas Negeri Medan

DOI:

https://doi.org/10.59581/konstanta.v2i2.3367

Keywords:

Alkaloid, Cinnamon, Soxhlet extraction, Mayer's reagent, Pharmaceutical development

Abstract

The study aimed to investigate the alkaloid content in cinnamon (Cinnamomum burmannii) powder using the Soxhlet extraction method. Alkaloids are organic chemical compounds widely found in nature as secondary metabolites in both plants and animals. They possess a cyclic structure containing one or more basic nitrogen atoms, conferring unique basic properties. The research was conducted to provide a deeper understanding of the potential utilization of plant-derived alkaloids, particularly from cinnamon, in drug development. The study sought to determine the color of the precipitate formed in the extraction solution after the addition of Mayer's reagent and to investigate the effect of the number of Soxhlet extraction cycles on the color of the ethanol used in the research with cinnamon samples. The findings from this study contribute to the exploration of the alkaloid content in cinnamon and its potential applications in pharmaceutical development.

References

Anggraini, R. D. D., Purwati, E., & Safitri, C. I. N. H. (2021, October). Formulasi dan Stabilitas Mutu Fisik Ekstrak Kayu Manis (Cinnamomum burmannii) sebagai Bedak Padat Antioksida. In Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) (pp. 603-610).

Dillasamola,D.,dan Putri,B.O.(2023). Peronema canescens Jack Terhadap Hiperurisemia.Indramayu : Penerbit Adab.

Dwika, W., Putra, P., Agung, A., Oka Dharmayudha, G., & Sudimartini, L. M. (2016). Identifikasi Senyawa Kimia Ekstrak Etanol Daun Kelor (Moringa Oleifera L) Di Bali (Identification Of Chemical Compounds Ethanol Extract Leaf Moringa (Moringa Oleifera L) In Bali). Indonesia Medicus Veterinus

Maisarah, M., & Chatri, M. (2023). Karakteristik dan Fungsi Senyawa Alkaloid sebagai Antifungi pada Tumbuhan. Jurnal Serambi Biologi, 8(2), 231-236.

Marliana, S. D., Suryanti, V., & Suyono, S. (2005). Skrining fitokimia dan analisis kromatografi lapis tipis komponen kimia buah labu siam (Sechium edule Jacq. Swartz.) dalam ekstrak etanol. Biofarmasi, 3(1), 26-31.

Mayefis,d., S.Farm.,Jannah,N.R.,Nurhasnawati,H.,dan Hernahadini,N.(2023). KIMIA FARMASI KUALITATIF : Teori dan Analisa Komprehensif.Jakarta : PT. Sonpedia Publishing Indonesia.

Olofinsan, K., Abrahamse, H., & George, B. P. (2023). Therapeutic role of alkaloids and alkaloid derivatives in cancer management. Molecules, 28(14), 5578. Oktober, 5(5), 464-473.

Purwayantie,S.,Saputri,N.E.,dan Elviyanti.(2023). Mutu Ekstrak Alkaloid Daun Kratom (Mitragyna speciosa) dengan Sonikasi Tipe-Bath.Jakarta :Penerbit NEM.

Prasetyorini, U., NF, Y., Novitasari, N., & Fitriyani, W. (2021). Potensi Ekstrak Refluks Kulit Batang Kayu Manis (Cinnamomum burmannii) sebagai Antijamur Candida albicans dan Candida tropicalis. Fitofarmaka J. Ilm. Farm, 11, 164-178.

Ridwan, I., Meylin, M., Puspitasari, R., Dewi, D. R., & Ghozali, M. (2015). Pembuatan Biodiesel dengan Proses Ekstraksi Reaktif dari Ampas Perasan Kelapa. Fluida, 11(2), 22-26.

Riniati, R., Sularasa, A., & Febrianto, A. D. (2019). Ekstraksi kembang sepatu (Hibiscus Rosa Sinensis L) menggunakan pelarut metanol dengan metode sokletasi untuk indikator titrasi asam basa. Indonesian Journal of Chemical Analysis (IJCA), 2(01), 34-40.

Tok, T. T., & Gowder, S. J. (2019). Structural and pharmacological properties of alkaloids with special reference to thebaine type alkaloids. Biomedical Journal of Scientific & Technical Research, 17(3), 12767-12780

Wardhani, L. K., & Sulistyani, N. (2012). Uji aktivitas antibakteri ekstrak etil asetat daun binahong (Anredera scandens (L.) moq.) terhadap Shigella flexneri beserta profil kromatografi lapis tipis. Jurnal Ilmiah Kefarmasian, 2(1), 1-6.